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HIV Status Predictive Modeling Using Data Minin...
68,00 € *
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This research work has attempted to investigate the underlying determinant factors of being HIV positive or HIV negative from the available HCT data using data mining techniques. It consists of experiments on searching classification model that predicts HIV status and association rule mining to discover the relationship of HIV status with the selected attributes. The classification experiments are carried out using J48 and ID3 algorithms. The association rule mining is using Apriori algorithm. One of the surprising results obtained from the experiment was that age group 50 and above are becoming also vulnerable to HIV/AIDS as the patterns have indicated. Medical experts also have stated that a growing number of older people are being infected with HIV/AIDS. One of the reasons they raised is that, they are finding HIV more often than ever before in older age since improved treatments are helping people with the disease live longer. The second reason is doctors do not always test older people for HIV/AIDS and so may miss some cases during routine check-ups and others.

Anbieter: Dodax
Stand: 22.09.2020
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Molecular Therapy and Nanocarrier Based Drug De...
68,00 € *
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Worldwide, a number of research groups are functioning towards effective treatment of colon cancer using chemotherapeutic agents. Nonsteroidal anti-inflammatory drugs are among the most potent agents discovered for the inhibition of cancer. In spite of the approval of celecoxib for adjuvant therapy in patients with familial adenomatous polyposis and precancerous disease of colon, associations of larger intensity of side effects limit its usage in cancer therapy. Combination therapy provides advantages of reduction in dose and possible reduction in toxicity and acquired drug resistance. As a consequence, targeted drug delivery and targeted molecular therapy of single or combination of anticancer agents are necessary for efficient treatment of colon cancer with reduced toxicity. In our study, combination of celecoxib and AEE788 shows growth inhibition and apoptosis in HCT 15 cells. Further, nanocarrier mediated celecoxib delivery showed high entrapment efficiency, sustained release patterns, desirable hemocompatibility and enhanced cytotoxicity and apoptosis in vitro and in vivo.

Anbieter: Dodax
Stand: 22.09.2020
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Cost-effective Biomarkers in the Management of ...
39,90 € *
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The disease burden of human immunodeficiency virus (HIV) is substantially more prevalent among residents of the sub-Saharan Africa and Asia. The availability and affordability of highly active antiretroviral therapy (HAART) have significantly reduced the mortality among HIV-1 infected population, increase their life expectancy and quality of life. However, the poor financial conditions and lack of costly infrastructure in the developing countries hinder regular monitoring of HIV-1 RNA (viral load) and CD4+ T-lymphocyte cell count (TCD4+ cell count). Under these circumstances, there is an increasing need for alternate biomarkers for monitoring the progression of the disease and patient management. Albumin, hemoglobin (Hb), dehydroepiandrosterone sulfate (DHEA-S), red blood cell (RBC) count, erythrocyte sedimentation rate (ESR), plasma highly-sensitive C-reactive protein (hs-CRP), hematocrit (Hct), total lymphocyte count (TLC) are some of the alternate biomarkers with proven utility in the assessment of disease progression.

Anbieter: Dodax
Stand: 22.09.2020
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Health Care Transition
94,98 € *
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This comprehensive book thoroughly addresses all aspects of health care transition of adolescents and young adults with chronic illness or disability, and includes the framework, tools and case-based examples needed to develop and evaluate a Health Care Transition (HCT) planning program that can be implemented regardless of a patient's disease or disability. Health Care Transition: Building a Program for Adolescents and Young Adults with Chronic Illness and Disability is a uniquely inclusive resource, incorporating youth/young adult, caregiver, and pediatric and adult provider voices and perspectives. Part I of the book opens by defining Health Care Transition, describing the urgent need for comprehensive transition planning, barriers to HCT and then offering a framework for developing and evaluating health care transition programs. Part II focuses on the anatomic and neuro-chemical changes that occur in the brain during adolescence and young adulthood, and how they affect function and behavior. Part III covers the perspectives of important participants in the HCT transition process - youth and young adults, caregivers, and both pediatric and adult providers. Each chapter in Part IV addresses a unique aspect of developing HCT programs. Part V explores various examples of successful transition from the perspective of five key participants in the transition process - patients, caregivers, pediatric providers, adult providers and third party payers. Related financial matters are covered in part VI, while Part VII explores special issues such as HCT and the medical home, international perspectives, and potential legal issues. Models of HCT programs are presented in Part VIII, utilizing an example case study. Representing perspectives from over 75 authors and more than 100 medical centers in North America and Europe, Health Care Transition: Building a Program for Adolescents and Young Adults with Chronic Illness and Disability is an ideal resource for any clinician, policy maker, caregiver, or hospitalist working with youth in transition.

Anbieter: Dodax
Stand: 22.09.2020
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The Rhesus Negative Pregnant Mothers and Haemol...
15,90 CHF *
zzgl. 3,50 CHF Versand

Project Report from the year 2010 in the subject Medicine - Public Health, , course: Blood Transfusion, language: English, abstract: A total of 27 blood specimen of neonates born at the maternity section of central Hospital Porto Novo by the Rhesus Negative mothers were studied for a period of 12 months. The specimen collection were done within 72 hours of birth, mothers pregnant for the first time without a past history of abortion or transfusion were rejected for the study. Ten (10) blood specimens of the neonates were Rhesus blood group negative and were eliminated from the work whereas the remaining seventeen (17) were recorded Rhesus blood group positive. The results of the 17 specimen of neonates all recorded in mean values showed Hb 17. 23g/dl, Hct 51.56L/L, the mean cell volume was 102.18 FL, mean cell hemoglobin concentration was 33.41% and mean cell hemoglobin recorded 34.12 pg. The red cell count and white cell count were 5.04 × 10 12/L and 16.06 ×10 9/L respectively. The platelet count was 316.53 and red cell distribution width of 17.76% was recorded. The differential leucocytes counts were; Neutrophils 65.35%, Lymphocytes 25.71% and MXD (comprises of monocytes, eosinophils and basophils) recorded 13.48%. The mean results of Bilirubin direct and Bilirubin total were 0.76mg/dl and 4.29mg/dl. The Direct Coombs test (DCT) was positive in one specimen of neonates and this specimen showed Hb value of 13.6g/dl and a total Bilirubin of 27.5mg/dl. All the neonates were of full term with birth weight of 2.5 to 3.5 kg. This work serves as an epidemiological vigilance for haemolytic diseases of the newborn in the Porto Novo province. The incidence of hemolytic Disease of newborn in Porto Novo district was recorded to be 5.8% considering from this work where only a case gave positive Direct Coombs. Although, this work suffers from scarcity of pregnant mothers of Rhesus blood group negative and affects the research because the specimen collected were small for the time period of the work. The Porto Novo experience also showed that good control system is at work by the medical team and technical staff concerned with the testing of all prospective mothers. Another positive aspect is that anti-D is freely and timely available for mothers of D- positive infants and with persistent effort in this regard, the incidence should continue very low or until there is no more case of hemolytic disease of the newborn.

Anbieter: Orell Fuessli CH
Stand: 22.09.2020
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The Rhesus Negative Pregnant Mothers and Haemol...
6,40 CHF *
ggf. zzgl. Versand

Project Report from the year 2010 in the subject Medicine - Public Health, , course: Blood Transfusion, language: English, abstract: A total of 27 blood specimen of neonates born at the maternity section of central Hospital Porto Novo by the Rhesus Negative mothers were studied for a period of 12 months. The specimen collection were done within 72 hours of birth, mothers pregnant for the first time without a past history of abortion or transfusion were rejected for the study. Ten (10) blood specimens of the neonates were Rhesus blood group negative and were eliminated from the work whereas the remaining seventeen (17) were recorded Rhesus blood group positive. The results of the 17 specimen of neonates all recorded in mean values showed Hb 17. 23g/dl, Hct 51.56L/L, the mean cell volume was 102.18 FL, mean cell hemoglobin concentration was 33.41% and mean cell hemoglobin recorded 34.12 pg. The red cell count and white cell count were 5.04 × 10 12/L and 16.06 ×10 9/L respectively. The platelet count was 316.53 and red cell distribution width of 17.76% was recorded. The differential leucocytes counts were; Neutrophils 65.35%, Lymphocytes 25.71% and MXD (comprises of monocytes, eosinophils and basophils) recorded 13.48%. The mean results of Bilirubin direct and Bilirubin total were 0.76mg/dl and 4.29mg/dl. The Direct Coombs test (DCT) was positive in one specimen of neonates and this specimen showed Hb value of 13.6g/dl and a total Bilirubin of 27.5mg/dl. All the neonates were of full term with birth weight of 2.5 to 3.5 kg. This work serves as an epidemiological vigilance for haemolytic diseases of the newborn in the Porto Novo province. The incidence of hemolytic Disease of newborn in Porto Novo district was recorded to be 5.8% considering from this work where only a case gave positive Direct Coombs. Although, this work suffers from scarcity of pregnant mothers of Rhesus blood group negative and affects the research because the specimen collected were small for the time period of the work. The Porto Novo experience also showed that good control system is at work by the medical team and technical staff concerned with the testing of all prospective mothers. Another positive aspect is that anti-D is freely and timely available for mothers of D- positive infants and with persistent effort in this regard, the incidence should continue very low or until there is no more case of hemolytic disease of the newborn.

Anbieter: Orell Fuessli CH
Stand: 22.09.2020
Zum Angebot
The Rhesus Negative Pregnant Mothers and Haemol...
9,30 € *
zzgl. 3,00 € Versand

Project Report from the year 2010 in the subject Medicine - Public Health, , course: Blood Transfusion, language: English, abstract: A total of 27 blood specimen of neonates born at the maternity section of central Hospital Porto Novo by the Rhesus Negative mothers were studied for a period of 12 months. The specimen collection were done within 72 hours of birth, mothers pregnant for the first time without a past history of abortion or transfusion were rejected for the study. Ten (10) blood specimens of the neonates were Rhesus blood group negative and were eliminated from the work whereas the remaining seventeen (17) were recorded Rhesus blood group positive. The results of the 17 specimen of neonates all recorded in mean values showed Hb 17. 23g/dl, Hct 51.56L/L, the mean cell volume was 102.18 FL, mean cell hemoglobin concentration was 33.41% and mean cell hemoglobin recorded 34.12 pg. The red cell count and white cell count were 5.04 × 10 12/L and 16.06 ×10 9/L respectively. The platelet count was 316.53 and red cell distribution width of 17.76% was recorded. The differential leucocytes counts were; Neutrophils 65.35%, Lymphocytes 25.71% and MXD (comprises of monocytes, eosinophils and basophils) recorded 13.48%. The mean results of Bilirubin direct and Bilirubin total were 0.76mg/dl and 4.29mg/dl. The Direct Coombs test (DCT) was positive in one specimen of neonates and this specimen showed Hb value of 13.6g/dl and a total Bilirubin of 27.5mg/dl. All the neonates were of full term with birth weight of 2.5 to 3.5 kg. This work serves as an epidemiological vigilance for haemolytic diseases of the newborn in the Porto Novo province. The incidence of hemolytic Disease of newborn in Porto Novo district was recorded to be 5.8% considering from this work where only a case gave positive Direct Coombs. Although, this work suffers from scarcity of pregnant mothers of Rhesus blood group negative and affects the research because the specimen collected were small for the time period of the work. The Porto Novo experience also showed that good control system is at work by the medical team and technical staff concerned with the testing of all prospective mothers. Another positive aspect is that anti-D is freely and timely available for mothers of D- positive infants and with persistent effort in this regard, the incidence should continue very low or until there is no more case of hemolytic disease of the newborn.

Anbieter: Thalia AT
Stand: 22.09.2020
Zum Angebot
The Rhesus Negative Pregnant Mothers and Haemol...
4,99 € *
ggf. zzgl. Versand

Project Report from the year 2010 in the subject Medicine - Public Health, , course: Blood Transfusion, language: English, abstract: A total of 27 blood specimen of neonates born at the maternity section of central Hospital Porto Novo by the Rhesus Negative mothers were studied for a period of 12 months. The specimen collection were done within 72 hours of birth, mothers pregnant for the first time without a past history of abortion or transfusion were rejected for the study. Ten (10) blood specimens of the neonates were Rhesus blood group negative and were eliminated from the work whereas the remaining seventeen (17) were recorded Rhesus blood group positive. The results of the 17 specimen of neonates all recorded in mean values showed Hb 17. 23g/dl, Hct 51.56L/L, the mean cell volume was 102.18 FL, mean cell hemoglobin concentration was 33.41% and mean cell hemoglobin recorded 34.12 pg. The red cell count and white cell count were 5.04 × 10 12/L and 16.06 ×10 9/L respectively. The platelet count was 316.53 and red cell distribution width of 17.76% was recorded. The differential leucocytes counts were; Neutrophils 65.35%, Lymphocytes 25.71% and MXD (comprises of monocytes, eosinophils and basophils) recorded 13.48%. The mean results of Bilirubin direct and Bilirubin total were 0.76mg/dl and 4.29mg/dl. The Direct Coombs test (DCT) was positive in one specimen of neonates and this specimen showed Hb value of 13.6g/dl and a total Bilirubin of 27.5mg/dl. All the neonates were of full term with birth weight of 2.5 to 3.5 kg. This work serves as an epidemiological vigilance for haemolytic diseases of the newborn in the Porto Novo province. The incidence of hemolytic Disease of newborn in Porto Novo district was recorded to be 5.8% considering from this work where only a case gave positive Direct Coombs. Although, this work suffers from scarcity of pregnant mothers of Rhesus blood group negative and affects the research because the specimen collected were small for the time period of the work. The Porto Novo experience also showed that good control system is at work by the medical team and technical staff concerned with the testing of all prospective mothers. Another positive aspect is that anti-D is freely and timely available for mothers of D- positive infants and with persistent effort in this regard, the incidence should continue very low or until there is no more case of hemolytic disease of the newborn.

Anbieter: Thalia AT
Stand: 22.09.2020
Zum Angebot