Ihr Hct Shop

A Measure of Trust
68,00 € *
ggf. zzgl. Versand

The definition and measurement of human-computer trust (HCT) was addressed in this book in an exploration of trust as a general human experience and as an outcome of computer-aided decision-making. Trusting computer systems is an increasingly important issue for systems researchers, developers and users due to current market demands to provide and access information and business electronically and the trend toward automation through the use of intelligent systems. There has been little consistency to date in existing HCT research. Neither a robust definition of HCT nor a well-designed psychometric instrument for HCT could be found. This book, therefore, aims to contribute to a better understanding of the nature and structure of HCT and to provide a carefully designed and tested instrument for the measurement of HCT within the context of computer-aided decision-making.

Anbieter: Dodax
Stand: 26.02.2020
Zum Angebot
RNA interference Screens as a Tool for Discover...
79,00 € *
ggf. zzgl. Versand

Recent advances in the field of RNA interference (RNAi) have enabled researchers to conduct in depth investigations of gene function using RNAi libraries. Our second-generation shRNA libraries consist of over 200,000 short hairpin RNA constructs targeting over 45,000 human and mouse genes modeled after primary miRNA transcripts. Each hairpin is linked to a unique 60 nucleotide identification sequence, which serves as a barcode and allows us to virtually count the number of cells that contain a specific hairpin in a cell population. Small changes in barcode copy number can be monitored through the use of microarray technology. The barcode can be amplified from a cell's genomic DNA and fluorescently labeled to produce a probe that is hybridized to a microarray. I applied this RNAi barcode screening method in a screen using a complex mixture of 7500 library hairpins in a p53 isogenic HCT 116 colon cancer cells to identify genes that modify sensitivity to a common chemotherapeutic, doxorubicin. This work illustrates the powerful use of RNAi screens to search for genes that synergize with existing therapeutics, and suggests strategies for genetically informed combination therapies.

Anbieter: Dodax
Stand: 26.02.2020
Zum Angebot
Molecular Therapy and Nanocarrier Based Drug De...
68,00 € *
ggf. zzgl. Versand

Worldwide, a number of research groups are functioning towards effective treatment of colon cancer using chemotherapeutic agents. Nonsteroidal anti-inflammatory drugs are among the most potent agents discovered for the inhibition of cancer. In spite of the approval of celecoxib for adjuvant therapy in patients with familial adenomatous polyposis and precancerous disease of colon, associations of larger intensity of side effects limit its usage in cancer therapy. Combination therapy provides advantages of reduction in dose and possible reduction in toxicity and acquired drug resistance. As a consequence, targeted drug delivery and targeted molecular therapy of single or combination of anticancer agents are necessary for efficient treatment of colon cancer with reduced toxicity. In our study, combination of celecoxib and AEE788 shows growth inhibition and apoptosis in HCT 15 cells. Further, nanocarrier mediated celecoxib delivery showed high entrapment efficiency, sustained release patterns, desirable hemocompatibility and enhanced cytotoxicity and apoptosis in vitro and in vivo.

Anbieter: Dodax
Stand: 26.02.2020
Zum Angebot
Höfner Shorty BK E-Bass
139,00 € *
ggf. zzgl. Versand

Der Höfner Shorty Bass bietet eine Full-Scale-Mensur bei allerkleinsten Abmessungen: damit ist der Bass überall dabei. Der Shorty Bass HCT-SHB-BK in schwarz hat eine 76cm (30") Mensur und einen normalbreiten Hals. Um den Shorty unterwegs immer dabei zu haben, gehört auch ein passendes Gigbag zum Lieferumfang. · Bauart: Solid Body · Farbe: Black · Halskonstruktion: verschraubt · Mensur: Shortscale · Mensur: 30" (76,20 cm) · Hals: Ahorn (Maple) · Griffbrett: Palisander (Rosewood) · Bundanzahl: 24 · Griffbrett Einlagen: Dot Inlays · Saitenanzahl: 4-saitig · Pickuptyp: Humbucker · Hardware: Nickel · Lieferumfang: Gigbag · Produktionsland: China E-Bass

Anbieter: Musik Produktiv
Stand: 26.02.2020
Zum Angebot
Beurer MC 5000 HCT
1.480,42 € *
ggf. zzgl. Versand

Massagesessel / Bezugsmaterial Kunstleder / 61 kg / Netz / Knetmassage / Klopfmassage / Shiatsu-Massage / Rollenmassage / für den ganzen Körper

Anbieter: idealo
Stand: 26.02.2020
Zum Angebot
Phytate to kill cancer: Interactions of phytic ...
71,90 € *
ggf. zzgl. Versand

Phytic acid is extensively known for its anti-nutritional properties. The wide notion about this compound is to be changed totally. Hence, the study is focused on bringing out its potential as a drug molecule. The knowledge gained by understanding the binding efficacy of phytic acid and its analogues can help in the development of a new lead molecule. The antibacterial studies and cell line studies using HCT-15 confirmed the drugability. The potency of cancer drug targets can also be screened using docking studies. The entire work can bring out an effective lead molecule which maybe subjected to clinical trials. It is hypothesized that phytic acid and its derivatives having one or more of the following chemical functional groups such as the number of phosphates, phospho-diesters, charged phosphates, halogens, heavy atoms, steriocentred atoms, hydoxyl groups, hydrogen donors and acceptors, have an effect on the binding affinity towards the selected targets. Although, there are few reports to suggest the anticancer activity of PA, there is no work on its structure-activity relationship.

Anbieter: Dodax
Stand: 26.02.2020
Zum Angebot
Blutzuckermessgerät GlucoCheck GOLD Starter-Set...
26,90 € *
zzgl. 5,95 € Versand

Dieses Blutzuckermessger&auml t macht Ihnen die Blutzuckermessung besonders einfach und l&auml sst sich in den verschiedensten Lebenssituationen m&uuml helos einsetzen. Dank hintergrundbeleuchtetem Display und 1-Tasten-Bedienung k&ouml nnen Sie Ihren Blutzucker messen, wann und wo Sie wollen und erhalten innerhalb von nur 5 Sekunden Ihr Ergebnis. Blutzuckermessger&auml t mit beleuchtetem Teststreifeneinschub Der Teststreifeneinschub bei diesem Diabetes Messger&auml t ist beleuchtet, sodass Sie selbst bei schwierigen Lichtverh&auml ltnissen leicht den Einschub finden. Sie stecken den Teststreifen in Ihr Zuckermessger&auml t und erhalten Ihr Ergebnis einfach durch Tastendruck. Das Kodieren erfolgt dabei automatisch, sodass Ihnen die Blutzuckermessung deutlich vereinfacht wird. Fehler, wie sie bei der manuellen Kodierung entstehen k&ouml nnen, werden vermieden und Sie k&ouml nnen sofort mit der Messung beginnen. Das Blutzuckermessger&auml t ist zudem mit einer Teststreifenauswurftaste ausgestattet, die eine hygienische Entsorgung des Teststreifens erm&ouml glicht. Aktiv mit Diabetes leben Die einfache Bedienung, der beleuchtete Teststreifeneinschub und das beleuchtete Display machen dieses Blutzuckermessger&auml t zum zuverl&auml ssigen Begleiter im Alltag &ndash sei es auf langen Spazierg&auml ngen oder im Kino. Zu jeder Tageszeit k&ouml nnen Sie Ihre Ergebnisse leicht ablesen und so unbeschwert Ihre Freizeit genie&szlig en. Dank des anwenderfreundlichen Designs und des breiten H&auml matokrit-Bereiches ist das Blutzuckermessger&auml t f&uuml r jeden geeignet &ndash f&uuml r &auml ltere Diabetes-Patienten mit weiteren Krankheiten, wie zum Beispiel Lungenerkrankungen, ebenso wie f&uuml r Schwangere mit Schwangerschaftsdiabetes. Ihre Messdaten k&ouml nnen Sie per Bluetooth oder USB-Anschluss auf Ihren PC oder die DIAmant-App &uuml bertragen. Die Qualit&auml tsmerkmale des Blutzuckermessger&auml tes im &Uuml berblick: Blutzuckermessger&auml t zur Bestimmung der Glukose aus dem Kapillarblut Breiter H&auml matokrit-Bereich: 0 bis 70&nbsp % Beleuchteter Teststreifeneinschub Hintergrundbeleuchtetes Display Einfache Ein-Tasten-Bedienung (keine Kodierung erforderlich) Messdaten per USB-Anschluss oder Bluetooth auf PC oder Smartphone &uuml bertragbar HCT-Korrektur Durchschnittswerte: 14, 21, 28, 60 und 90 Tage

Anbieter: aktivshop
Stand: 26.02.2020
Zum Angebot
Medicinal application of spirooxindole based an...
39,90 € *
ggf. zzgl. Versand

The chemistry and an extensive spectrum of biological activities of spirooxindole have been examined since several decades and this heterocyclic core has received emerging consensus. This content aims to summarize recent advances made towards the discovery of Antituberculosis activity, AChE and BChE inhibitory activity, Anti-tumor activity, Antibacterial and Antifungal activity and Miscellaneous Activity holding spirooxindole as a nucleus with the substitution of several types of nucleophiles, and molecular patterns associated with particular potency have been identified targeting several Gram-positive and Gram-negative bacteria and some fungal species, mycobacterium tuberculosis H37Rv, and drug-resistant tuberculosis (XDR-TB), Alzheimer's disease, HCT 116 (colon), MCF 7 (Brest) and HEPG 2 (liver) human tumor cell lines. The report will be of enormous interest to gain useful information for the furtherance of drug discovery with extended spirooxindole designs.

Anbieter: Dodax
Stand: 26.02.2020
Zum Angebot
Pharmacological investigations on Melochia corc...
35,90 € *
ggf. zzgl. Versand

This research work was carried out to establish scientific based evidence on folkloric usage and knowledge. The aim of this work is Pharmacological evaluation of Melochia corchorifolia leaves (folkloric) for antioxidant, diuretic, antiurolithiatic, anticancer, antibacterial and anthelmintic activities. In this regard, Melochia corchorifolia leaves were extracted with chloroform and ethylalcohol. The obtained extracts were used for pharmacological activities, the antioxidant activity results, the extracts and its Phenolic content shows good averting activity. Diuretic and saluretic activity is due to altering renal sodium excretion.The antiurolithiatic activity may be due to the presence of secondary metabolites of the extract.The extracts produced good anticancer activity on HCT-116 cell line and MCF-07 cancer cell lines. The chloroform extracts of Melochia corchorifolia shows good antibacterial and anthelmintic activities. So it was concluded that this research work supports the folkloric usage of this herbal drug (Melochia corchorifolia) is a potential source for treating various ailments.

Anbieter: Dodax
Stand: 26.02.2020
Zum Angebot
Antimicrobial and antitumor substance(s) produc...
61,90 € *
ggf. zzgl. Versand

The emergence of extensive antibiotics resistant bacteria increased the demands for find out new source of antimicrobial agent, Actinomycetes, especially Streptomycetes spp have recently grasped considerable attention worldwide due to production of many useful bioactive metabolites that exploited by the pharmaceutical industry. In present study, a number of 52 Actinomycetes were recovered, from which 20 showed antimicrobial activities to at least one tested organism. The most potent isolate AGM12-1, which was active against all tested organisms and with IC50 3.3 and 1.1mig/ml. against HCT 116 and HepG-2 respectively was characterized as Streptomyces vinaceusdrappus with presence of ARO-PKS II genes. Mannitol, ammonium sulfate, pH 7, 2% stating inoculums and incubation for 11 days at 30°c were the optimum conditions used to maximize the production and hence allowed purification of one active compound to homogeneity using RP-HPLC with m/z 488.05.The NMR structural elucidation showed that this compound was a derivative of Diketopiperazine.

Anbieter: Dodax
Stand: 26.02.2020
Zum Angebot
Increasing Emiratisat'ion in engineerin'g facul...
33,90 € *
ggf. zzgl. Versand

Increasing Emiratisat'ion in engineerin'g faculty position at the HCT ab 33.9 EURO

Anbieter: ebook.de
Stand: 26.02.2020
Zum Angebot
Jammu Botanicals In The Management Of Cancer
39,90 € *
ggf. zzgl. Versand

Cancer is one of the most dreaded diseases responsible for millions of deaths every year. In the present study, 12 medicinal plants from Jammu region, viz., Alstonia scholaris (devil tree), Azadirachta indica (neem), Calotropis gigantea (milk weed), Emblica officinalis (amla), Mentha citrata (bergamot mint), Mentha piperita (piper mint), Mentha viridis (pudina), Murraya koengii (kari pata), Musa paradisiaca (banana), Olea europaea (olive), Punica garanatum (pomegranate) and Trachyspermum ammi (ajwain) were evaluated against five human cancer cell lines from four different origins, viz., A-549 (lung), HCT-116 (colon), MCF-7 (breast), PC-3 (prostate) and T-47D (breast). 7 medicinal plants showed in vitro cytotoxic effect against one or the other human cancer cell line with the remarkable results produced by Calotropis gigantea (73-78% growth inhibition at 10 mig/ml against lung, colon and prostate cancer cells).To conclude, the plant can provide a great service and promise to cancer patients.

Anbieter: Dodax
Stand: 26.02.2020
Zum Angebot

Stöbern Sie durch unser Sortiment


Alle Angebote

Eine Auswahl unserer Shops

Häufig gesucht